The presence of rhupus and AHA is an extremely uncommon condition, with only a few cases previously reported. Autoimmune hemolytic anemia (AHA) presents in approximately 1/10 patients with SLE, but is a very uncommon process in RA. Lupus arthropathy is a nonerosive process and is relatively a common manifestation of SLE however, approximately 1% of patients with SLE will develop erosive arthropathy, which is difficult to differentiate from AR arthropathy. The term “rhupus” describes a syndrome that comprises the coexistence of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). We report a rare case of rhupus in a 29-year-old woman, associated with autoimmune hemolytic anemia. ![]() There are few reported cases of the association between autoimmune hemolytic anemia and rheumatoid arthritis with systemic lupus erythematosus (rhupus). “Rhupus” syndrome is a rare condition that describes the coexistence of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), which prevalence among patients with SLE varies from 0.01% to 9.7%.
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